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循环肿瘤细胞与肿瘤干细胞相关性的研究进展 被引量:1

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摘要 肿瘤的转移是一个涉及多步骤、多因素的复杂过程,近年来研究发现肿瘤的微转移是其早期事件。目前已证实循环肿瘤细胞(circulatingtumorcells,CTCs)可能是转移的起源,在肿瘤转移的环节中扮演重要角色。肿瘤干细胞(cancerstemceils,CSCs)是肿瘤组织内少量可以自我复制的肿瘤细胞,在肿瘤发生、发展和转移、复发中起主导作用。CTCs在外周血中数量较少,目前有文献报道CTCs具有肿瘤干细胞的特性,这将为今后靶向CTCs的治疗提供新的靶点。故本文就CTCs与CSCs的相关性进行综述,以期为预防肿瘤转移提供新的思路。
出处 《中国综合临床》 2014年第8期894-896,共3页 Clinical Medicine of China
基金 天津市高等学校科技发展基金计划项目(20110130) 天津医科大学科技基金资助项目(2008ky08)
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