期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

A型胰岛素抵抗综合征及其临床处理 被引量：1

下载PDF
导出
摘要 A型胰岛素抵抗综合征（Insulin resistance type C syndrome），又称A型综合征，卵巢性高雄激素血症、胰岛素抵抗的黑棘皮病（HAIR—AN综合征，胰岛素抵抗性糖尿病A型。Flier于1975年首先报道一名女性，为伴有高度抵抗的黑棘皮病患者，Kahn于1976年证明体内胰岛素受体少而命名为A型综合征。
作者 梁丽 刘赫
机构地区 辽宁省人民医院内分泌 北京协和医院内分泌科
出处 《实用糖尿病杂志》 2014年第4期8-9,共2页 Journal of Practical Diabetology
关键词 胰岛素抵抗综合征 A型 临床处理 胰岛素抵抗性糖尿病 高雄激素血症 黑棘皮病 胰岛素受体 卵巢性
分类号 R587.1 [医药卫生—内分泌]
  • 相关文献

参考文献15

  • 1Flier JS, Kahn CR, Roth J. Receptors, antireceptor antibodies and the mechanism of insulin resistance N Engl J Med 1979;300: 413 -419.
  • 2Kahn CR, Insulin action diabetogenes, and the cause of type Ⅱ diabetes(Banting lecture). Diabetes 1994 ;43 : 1066 - 1084.
  • 3Yoshimasa Y, Seino S, wliittaker, et al. Insulin-resistant dia- bates due to a point mutation that prevents insulin proreceptor pro- cesing Science 1988,240:784 -787.
  • 4Kudowaki T, Berins CL, Cama A, et al. Two mutant alle Ies of the in sulin receptor gene in a patient with extreme insulin resist- ance. Science 1988 ;240:787 -790.
  • 5Whitehead JP, Soons MA, Jackson R, et al. Multiple molecu- lar mechanisms of insulin receptor dysfunction in a patient with Dono- hue syndronne. Diabetes 1998 ;47 : 1362 - 1364.
  • 6Longo N,Wang Y,Smith SA,et al. Genotype-phenotype eor- relation in inherited severe in sulin resistance. Hum Mol Genet 2003 ; 11 : 1465 - 1475.
  • 7庞璨,黄知敏,朱慧丽,余秋琼,严晋华,廖志红,胡国亮,翁建平.中国人A型胰岛素抵抗家系与胰岛素受体基因突变研究[J].中华内分泌代谢杂志,2005,21(3):237-239. 被引量：17
  • 8Mosthat L, Grako K, Dull TJ, et al. Functionally distince insu- lin receptors generated by tissue-specific altertive splicing. EMBOJ 1990;9:2409 -2413.
  • 9Wertheimer E, Lu SP, Backeljauw PF, et al. Homozygous de- letion of the human insulin receptor gene, Nat Genet 1993 ; 5 : 71 - 73.
  • 10Kadomaki T, Kodowaki H, AcciliD, et al. Substitution of ly- sine for as paragines at position 15 in the alpha-subunit of the human in sulin receptor a mutation that impairs transport of insulin to the cell surface and decreases the affinity of insulin binding. J Biol chem 1990 ;256 : 19143 - 150.

二级参考文献43

  • 1Moller DE, Yokota A, Caro JF, et al. Tissue-specific expression of two alternatively spliced insulin receptor mRNAs in man. Mol Endocrinol, 1989,3:1263-1269.
  • 2Yoshimasa Y, Seino S, Whittaker J, et al. Insulin-resistant diabetes due to a point mutation that prevents insulin proreceptor processing. Science, 1988,240:784-787.
  • 3Kadowaki T, Bevins CL, Cama A, et al. Two mutant alleles of the insulin receptor gene in a patient with extreme insulin resistance. Science, 1988,240:787-790.
  • 4Seino S, Seino M, Bell GI. Human insulin-receptor gene. Partial sequence and amplification of exons by polymerase chain reaction. Diabetes, 1990,39:123-128.
  • 5Whitehead JP, Soons MA, Jackson R, et al. Multiple molecular mechanisms of insulin receptor dysfunction in a patient with Donohue syndrome. Diabetes, 1998,47:1362-1364.
  • 6Longo N, Wang Y, Smith SA, et al. Genotype-phenotype correlation in inherited severe insulin resistance. Hum Mol Genet, 2002,11:1465-1475.
  • 7Moller DE, Cohen O, Yamaguchi Y, et al. Prevalence of mutations in the insulin receptor gene in subjects with features of the type A syndrome of insulin resistance. Diabetes, 1994,43:247-255.
  • 8Kadowaki T, Kadowaki H, Rechler MM, et al. Five mutant alleles of the insulin receptor gene in patients with genetic forms of insulin resistance. J Clin Invest, 1990,86:254-264.
  • 9Kusari J, Takata Y, Hatada E, et al. Insulin resistance and diabetes due to different mutations in the tyrosine kinase domain of both insulin receptor gene alleles. J Biol Chem, 1991,266:5260-5267.
  • 10Ullrich A, Bell JR, Chen EY, et al. Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes. Nature, 1985,313:756-761.

共引文献17

同被引文献11

引证文献1

二级引证文献13

实用糖尿病杂志
2014年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部