248例过敏性疾病患儿血清特异性IgE抗体检测分析

Analysis on serum specific IgE antibody detection in 248 children patients with allergic diseases

目的检测过敏性疾病患儿血清过敏原特异性IgE,为过敏性疾病的临床诊断、治疗和预防提供依据。方法采用欧蒙印迹法检测248例年龄8个月至14岁的患儿的血清过敏原特异性IgE,并统计分析。结果 248例过敏性疾病患儿中,过敏性鼻炎、支气管哮喘以吸入性过敏原为主,其中以屋尘螨/粉尘螨阳性率最高,为54.2%,其次为蟑螂,阳性率为35.3%,荨麻疹、过敏性紫癜以食入性过敏原为主,其中蟹、海鱼阳性率较高,分别为43.2%和31.4%。结论吸入性过敏原中的屋尘螨/粉尘螨与食入性过敏原中的蟹、海鱼是本地区的主要过敏原,患儿应避免接触或摄入过敏原,以减少过敏性疾病的发生。

Objective To detect the serum allergen specific IgE in the children patients with allergic diseases to provide the basis for the clinical diagnosis,treatment and prevention of allergic diseases.Methods To detect the allergen specific IgE in 248 children patients（aged 8 months to 14 years old）with allergic diseases by the EUROLINE method.The detection results were statistically analyzed.Results Among 248 cases,allergic rhinitis（AR）and bronchial asthma were dominated by the inhalant allergens,in which the house dust mites/dust mites had the highest positive rate （86.9%）,followed by roach（45.3%）;urticaria and allergic purpura were dominated by food allergens,in which crab had the highest positive rate （43.2%）,followed by marine fish（31.4%）.Conclu-sion The house dust mites/dust mites in the inhalant allergens and crab and marine fish in the food allergens are the main allegens in Luzhou area,the children patients with allergic diseases should avoid to contact or intake the allergen in order to reduce the oc-curence of allergic disease.