非湿化低流量氧疗对AECOPD患者舒适度的影响

Effect of low-flow,dry oxygen therapy on comfort of patients with acute exacerbations of chronic obstructive pulmonary disease

目的探讨湿化与非湿化方式的持续低流量氧疗对慢性阻塞性肺疾病急性加重期(AECOPD)患者舒适度的影响。方法将200例接受低流量鼻导管氧疗的AECOPD患者按床号的单双数分为观察组(94例)和对照组(106例),对照组患者用气泡喷射式湿化装置吸氧,观察组直接接氧流量表吸氧。比较两组患者实施氧疗第3天、第5天主观不适症状(鼻部不适、咽喉部不适、头痛、胸部不适)及其严重程度。结果两组患者吸氧第3天、第5天不适症状评分比较,差异无统计学意义(均P>0.05)。结论非湿化低流量氧疗不影响AECOPD患者的舒适程度。

Objective To investigate whether patients with acute exacerbations of chronic obstructive pulmonary disease （AECOPD） requiring low flow oxygen would benefit from humidified oxygen when compared to dry oxygen therapy. Methods Two hundred pa- tients with AECOPD requiring nasal oxygen at low-flow rates were divided into a control group of 106 and an observation group of 94. The control group received humidified oxygen delivered by bubble-jet humidifiers, while the observation group received dry oxy- gen gas which was supplied through nasal cannula directly attached to the flow meter. Subjective complaints （nasal discomfort, throat discomfort, headache, and chest discomfort） and symptom severity on day 3 and day 5 were compared between the two groups. Results There were no statistical differences in discomfort symptoms on day 3 and day 5 between the two groups（P〉0.05 for all）. Conclusion Oxygen administered without prior humidification may not contribute to discomfort of patients with AECOPD.