梅毒合并感染肝炎患者乙肝病毒检测分析

The Analysis of Hepatitis B Virus Detection in Syphilis Patients with Hepatitis Infections

目的对梅毒合并感染肝炎患者乙肝病毒的感染情况进行调查分析,为临床研究提供有效的依据。方法选取2010年7月—2013年1月在该院治疗梅毒的患者166例,将其设为观察组;同期选取在该院健康体检患者402例,将其设为对照组。对两组患者进行乙肝病毒血清标志物检测。结果观察组中乙肝病毒感染率30.72%,"大三阳"的阳性率为50.98%,"小三阳"的阳性率为39.22%;对照组中乙肝病毒感染率17.91%,"大三阳"的阳性率为30.56%,"小三阳"的阳性率为55.55%。两组患者乙肝病毒携带率、"大三阳"的阳性率及"小三阳"的阳性率比较差异有统计学意义(P<0.05)。结论相对于健康患者,梅毒患者乙肝病毒的感染率较高,应对梅毒患者在乙肝病毒的传播上加以重视。

Objective To investigate and analyze the hepatitis B virus infection status of syphilis patients with hepatitis infections so as to provide an effective basis for the clinical research. Methods 166 cases of patients with syphilis admitted in our hospital from July, 2010 to January, 2013 were set as the observation group, and 402 cases of healthy controls underwent healthy examination in our hospital during the same period were set as the control group. The detection of serum markers of hepatitis B virus was performed in both groups of patients. Results Results The HBV infection rate in the observation group was 30.72%, HBsAg,HBeAg, and HBcAb test positive rate was 50.98%, HBsAg, HBeAb, and HBcAb test positive rate was 39.22%; the HBV infection rate in the control group was 17.91%, HBsAg, HBeAg, and HBcAb test positive rate was 30.56%, HBsAg, HBeAb, and HBcAb test positive rate was 55.55%, the differences in hepatitis B virus carrying rate, HBsAg, HBeAg, and HBcAb test positive rate and HBsAg, HBeAb, and HBcAb test positive rate between the two groups were statistically significant（P〈0.05）. Conclusion Compared to the healthy controls, the HBV infection rate of syphilis patients is higher, and we should pay more attention to the spread of hepatitis B virus in patients with syphilis.