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常用抗癫痫中药的研究模型及机制进展 被引量：3

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摘要 本文对近年来国内外报道的抗癫痫中药,癫痫模型及机制作一综述,以期为高效、低毒的抗癫痫药物的开发,提供一定的参考依据,为防治癫痫拓展新的思路。
作者 刘开庆 向诚 李鹏 李宝才
机构地区 昆明理工大学生命科学与技术学院 澳门大学中华医药研究院中药质量研究国家重点实验室
出处 《云南中医中药杂志》 2014年第7期76-78,共3页 Yunnan Journal of Traditional Chinese Medicine and Materia Medica
基金 国家自然科学基金项目(NO:C020601)
关键词 癫痫机制 癫痫模型 中药
分类号 R285.5 [医药卫生—中药学]
  • 相关文献

参考文献25

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二级参考文献43

  • 1杨蓉,王明正,成银霞,梁月琴.托吡酯对青霉素诱发大鼠痫性放电和海马区相关递质含量的影响[J].中国药理学通报,2005,21(1):99-102. 被引量：9
  • 2杨桂元,王玮.宽叶缬草治疗冠心病的临床研究[J].中国中西医结合杂志,1994,14(9):540-542. 被引量：24
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  • 7Jensen FE, Firkusny IR, Mower GD. Differences in c-fos immunoreactivity due to age and model of seizure induction. Mol Brain Res, 1993; 17(3-4) : 185.
  • 8Dragunow M, Yamada N, Bilkey DK, et al. Induction of immediate-early gene proteins in dentate granule cell and somatostatin intemeurons after hippocampal seizures. Mol Brain Res, 1992;13(1--2):119.
  • 9Honkamiemi J, Kononen J, Kainn T, et al. Induction of muliple immediate early genes in mt hypothalamic pareventricular nucleus after stress .Molecular Brain Research, 1994;25(3):234.
  • 10Morgan JI, Curran T. Immediate early gene: ten year on. TINS,1995 ; 18 : 66.

共引文献105

同被引文献20

  • 1Treiman DM. GABA ergic mechanisms in epilepsy[ J ]. Epilepsia, 2001,42(Suppl 3) :8 - 12.
  • 2Cho CH. New mechanism for glutamate hypothesis in epilepsy [ J ]. Frontiers in Cellular Neuroscience,2013,7 (33) :127.
  • 3Andr V, Dub C, Franols J, et al. Pathogenesis and pharmacology of epilepsy in the lithium- pilocarpine model[ J]. Epilepsia,2007,48 (Suppl 5) :41 -47.
  • 4Racine RJ. Modification of seizure activity by electrical stimulation lI. Motor seizure [ J ]. Electroencephalography and Clinical Neuro- physiology, 1972,32 ( 3 ) :281 - 294.
  • 5Parent JM, Elliott C, Pleasure SJ, et al. Aberrant seizure - induced neurogenesis in experimental temporal lobe epilepsy [ J ]. Annals of Neurology,2006,59 ( 1 ) : 81 - 91.
  • 6Narnba T, Mochizuki H, Onodera M, et al. The fate of neural progen- itor cells expressing astroeytic and radial glial markers in the post- natal rat dentate gyms[ J]. The European Journal of Neuroscienee, 2005,22 ( 8 ) : 1928 - 1941.
  • 7SHI Xiuyu, WANG Jiwen, LEI Gefei, et al. Morphological and be- havioral Consequences of recurrent seizures in neonatal rats are as- sociated with glucocorticoid levels [ J ]. Neuroscicnce Bulletin, 2007,23(2) :83 -91.
  • 8Walter C, Murphy BL, Pun RY, et al. Pilocarpine - induced sei- zures cause selective time dependent changes to adult generated hippocampal dentate granule ceils [ J ]. The Journal of Neuro- science ,2007,27 (28) :7541 - 7552.
  • 9方松,余化霖.Morris水迷宫实验中海马相关空间学习记忆的研究进展[J].国际病理科学与临床杂志,2010,30(4):321-326. 被引量：75
  • 10杨丽白,周列民.瑞替加滨在癫痫治疗中的作用机制及应用前景[J].中国神经精神疾病杂志,2011,37(2):124-127. 被引量：3

引证文献3

二级引证文献9

云南中医中药杂志
2014年 第7期

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