摘要
Objective To observe the effect of stimulating Yinttang （印堂 EX-HN 3） and Baihui（百会 GV 20） with electroacupuncture （EA） on blood oxygenation level of brain and explore the feasibility of measuring the therapeutic effect of acupuncture by applying near infra red spectrum （NIRS）. Methods Ten participants semi-randomly selected from 158 adults （random test sequence） were stimulated with EA at the acupoints of EX-HN 3 and GV 20. Verbal fluency task was conducted before and after acupuncture, and changes in blood oxygenation level of cerebral cortex were tested by applying NIRS. Quantitative data were processed with JMP 10.0.2 software, and changes in waveforms of blood oxygenation level of brain before and after treatment were compared by applying NIRS. Results ① The mean of reacting dose （integral value） of blood oxygenation level of cerebral cortex of the 158 adults in the verbal fluency task was 10.6 ± 1.1, and the mean of the whole reacting dose of blood oxygenation level of cerebral cortex at 1/2 period of time during the test （centroids value） was 46.8 ± 1.6. ② In the EA group, the mean of integral value and centroids value of 10 adults were 8.4 ± 5.1 and 54.7± 12.2 before EA while 9.8±3.5 and 41.2±6.7 after EA. The integral value and centroids value of the EA group were closer to the mean of all the subjects. Conclusion It was found by NIRS that the blood oxygenation level of cerebral cortex could be regulated in bi- directional way by stimulating EX-HN 3 and GV 20 with EA, and a further research on whether it directly related to EA is to be made.
目的:观察电针刺激印堂和百会穴对人脑血氧水平的影响,探讨应用近红外光成像技术(NIRS)测定针灸治疗作用的可行性。方法:158名成年人中半随机(测试顺序随机)选择10名予以电针印堂穴和百会穴刺激。于电针前后分别施行语言流畅性课题测试,并应用NIRS测试大脑皮层血氧浓度变化。应用JMP 10.0.2软件统计处理量化数据,应用NIRS比较电针前后脑内血氧水平的波形变化。结果:①语言流畅性课题中158名成年人大脑皮层脑血氧反应量(积分值)的平均值是10.6±1.1,语言流畅性课题前至课题结束后在大脑皮层脑血氧全反应量的第1/2时间(重心值)的平均值是46.8±1.6。②电针组10人电针前平均积分值和重心值平均为8.4±5.1,54.7±12.2。电针后积分值和重心值的平均为9.8±3.5,41.2±6.7。通过电针百会穴、印堂穴其积分值和重心值倾向于全体被试对象的平均值。结论:通过NIRS观察到电针刺激百会穴、印堂穴可以双向调节大脑皮层脑血氧水平,其是否定论为针刺效果尚须进一步研究。
