蒙药嘎日迪-15味丸治疗膝骨关节炎的临床研究

Clinical research on the treatment of Mongolian medicine GaRi-di 15 Flavors Pills for knee osteoarthritis

目的:研究蒙药嘎日迪-15味丸治疗膝骨关节炎的临床疗效。方法:将52例膝骨关节炎患者随机分为治疗组和对照组,每组26例。对照组用抗骨增生胶囊,5粒/次,3次/d,饭后服;治疗组在对照组基础上加用蒙药嘎日迪-15味丸,11粒/次,早、晚饭后服。两组治疗后第45天进行疗效比较,并对治疗前及治疗后第15、30、45天进行患膝症状评分,结果进行统计学分析,随访半年,比较复发率。结果:治疗组总有效率为88.0%,对照组为56.0%,治疗组优于对照组(P<0.05);治疗后第15天两组症状无显著差异,治疗组第30、45天的症状优于对照组(P<0.05);随访半年治疗组与对照组复发率分别为12.0%、48.0%,治疗组明显低于对照组(P<0.05)。结论:蒙药嘎日迪-15味丸治疗膝骨关节炎能有效缓解疼痛,改善关节功能,有较好的临床疗效。

Objective： To research the curative effect on the treatment of Mongolian prescription GaRi-di 15 Flavor Pills for knee osteoarthritis. Methods： 52 patients with knee osteoarthritis were randomly divided into treatment group and control group, with 26 cases in each group. The control group was given Kang Guzengsheng Capsule, 5 grains per time after meals, three times a day The treatment group was added with Mongolian GaRi-di15 Flavor Pills on the basis of control group, 11 grains per time, after breakfast and dinner. The curative effect was compared between the two groups on the 45 days after the treatment. The knee symptom scores were evaluated on the 15th, 30th, 45th day before and after treatment, the results were statistically analyzed, follow up visit for 6 months, and compared the recurrence rate. Results： Making comparison of the two groups of patients with clinical efficacy, the total effective rate was 88.0% in the treatment group and 56.0% in the control group. The treatment group was better than that in control group （P〈0.05）. Making comparison of the symptoms of the 15th day after treatment in two group, there was no significant difference. The symptoms of the 30th, 45th day in the treatment group were better than those in control group （P〈0.05）. Follow up visit for 6 months, the recurrence rate was 12.0% in the treatment group and 48.0% in the control group. The recurrence rate of the treatment group was significantly lower than that in control group （P〈0.05）. Conclusion： Mongolian medicine GaRi-dil5 Flavor Pills on the treatment of knee osteoarthritis could effectively relieve the pain and improve joint function, which had a good clinical curative effect.