抗抑郁护理在功能性便秘患者中的应用

Application of antidepressant nursing in patients with functional constipation

目的：分析探讨抗抑郁护理在功能性便秘疾病患者中的临床价值和意义。方法选择海军总医院2010年12月-2012年12月90例功能性便秘患者按住院号随机均分为3组，A组患者采用常规护理，同时给予小剂量帕罗西汀；B组患者行抗抑郁护理；C组患者采用常规护理。分别于治疗前及干预后1，2周对各组患者抑郁自评量表（ SDS）、焦虑自评量表（ SAS）及药物不良反应进行统计学分析。结果3组间患者入院时平均SDS、SAS评分水平，差异均无统计学意义（ F分别为0．280，1．286；P＞0．05，LSD法两两比较分析均P＞0．05）。入院1周A、B组SDS、SAS评分略低于C组，差异均无统计学意义（F分别为1．927，1．286；P＞0．05，且LSD法两两比较分析均P＞0．05）；入院2周A、B组SDS、SAS评分明显低于C组，差异有统计学意义（F分别为16．337，17．733，P＜0．05，LSD法分析A、C组，B、C组间比较P＜0．05）。析因实验方差分析SDS、SAS改变与不同抗抑郁干预方式-时间因素均存在差异（ F分别为66．744，12．806；P＜0．01），且存在交互作用。同时A组患者药物不良反应率明显高于B、C组患者，差异有统计学意义（χ2＝12．857，P＜0．01）。结论抗抑郁护理能明显缓解功能性便秘患者的焦虑、抑郁情绪及临床症状评分，并可有效避免抗抑郁药物引起的不良反应，具有重要的护理价值，值得临床推广。

Objective To investigate the clinical value and significance of antidepressant nursing in patients with functional constipation .Methods From December 2010 to December 2012 , 90 cases of functional＆amp;nbsp;constipation were randomly divided into three groups .Patients in group A were given routine nursing care and a small dose of paroxetine;patients in group B were treated with antidepressant; patients in group C were given routine nursing care .Before treatment , and after 1 week and 2 weeks of treatment , the Self Rating Depression Scale （ SDS） , the Self Rating Anxiety Scale （ SAS ） and adverse drug reactions were statistically analyzed . Results The scores of SDS and SAS among the three groups had no significant differences when patients first charged into the hospital （F=0.280, 1.286, respectively; P〉0.05 and LSD P〉0.05）.After 1 week of treatment, the SDS and SAS scores of group A and B were slightly lower than those in group C （ F=1.927, 1.286, respectively;P〉0.05 and LSD P〉0.05）, but there was no significant differences .After 2 weeks of treatment, the SDS and SAS scores of group A and B were significantly lower than those in group C （ F =16.337, 17.733, respectively; P 〈0.05 and LSD P 〈0.05 ）, indicating the existence of significant differences .Factorial analysis of variance results showed that the changes of SDS and SAS and the differences of antidepressant intervention method-time were different （F=66.744, 12.806, respectively;P〈0.01）, with an interaction.The incidence of adverse drug effect was significantly higher in group A than that in group B or group C （χ2 =12.857,P〈0.01）.Conclusions Antidepressant nursing can relieve anxiety and depression symptoms in patients with functional constipation , and can effectively avoid the adverse reaction induced by antidepressants , so it is worthy of the clinical promotion .