丹参川芎嗪注射液联合奥扎格雷钠治疗脑梗死的疗效观察

Effect observation of salviae miltiorrhizae and ligustrazine hydrochloride injection combined ozagrel in the treatment of cerebral thrombosis

目的观察丹参川芎嗪注射液联合奥扎格雷钠治疗脑梗死的临床疗效。方法选取脑梗死患者58例,随机分为对照组和治疗组各29例,2组均予降颅压、营养脑细胞等基础治疗,对照组加予丹参川芎嗪注射液进行治疗;治疗组在对照组基础上,加予奥扎格雷钠注射液。服药14d后对比分析其临床疗效。结果治疗组总有效率为93.1%明显高于对照组的82.8%,2组比较差异有统计学意义(P<0.05);2组均未出现明显不良反应。结论采用丹参川芎嗪注射液联合奥扎格雷钠治疗脑梗死,疗效显著,不良反应少,安全性高,值得临床推广应用。

Objective To investigate the clinical efficacy of salviae miltiorrhizae and ligustrazine hydrochloride injec-tion combined ozagrel in the treatment of cerebral thrombosis. Methods 58 cases of patients with cerebral thrombosis were randomly divided into control group and treatment group,each of 29 cases. The 2 groups were given basic treatment. The control group was given salviae miltiorrhizae and ligustrazine hydrochloride injection for treatment based on the basic treatment,while the treatment group was added ozagrel bases on the control group. The clinical efficacy was analyzed after taking 14d. Results The total effective rate（93. 1% ）of the treatment group was significantly higher than 82. 8% of the control group,the differ-ence was statistically significant（P ﹤ 0. 05）. There were no obvious adverse reactions in the 2 groups. Conclusion The effect of salviae miltiorrhizae and ligustrazine hydrochloride injection combined ozagrel is significant in the treatment of cerebral thrombosis,with fewer adverse reactions and higher security,which is worthy of clinical application.