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利福平辅助治疗耐药肺炎支原体肺炎疗效观察 被引量:2

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摘要 目的观察利福平联合阿奇霉素治疗耐药肺炎支原体肺炎疗效。方法将110例耐药肺炎支原体肺炎患儿随机分为观察组58例和对照组52例,对照组给予阿奇霉素治疗,观察组在治疗组基础上加用利福平治疗,观察临床症状、体征、X线、住院时间及临床效果。结果观察组临床症状、体征减轻和消失、胸片或肺CT阴影减轻或消失的时间明显少于对照组,平均住院天数短与对照组,差异有统计学意义(P<0.05)。观察组总有效率为96.6%明显优于对照组的84.6%,差异有统计学意义(P<0.05)。结论利福平联合阿奇霉素治疗耐药肺炎支原体肺炎,对缩短发热时间、减轻咳嗽等症状、促进啰音消失、降低平均住院日,有明显疗效,且用药安全,不良反应小,患儿及家长易接受,值得临床推广应用。
出处 《临床合理用药杂志》 2014年第20期45-46,共2页 Chinese Journal of Clinical Rational Drug Use
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