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树突状细胞在变应性鼻炎舌下免疫治疗中的作用机制 被引量:4

The effect of dendritic cells on allergic rhinitis in sublingual therapy
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摘要 树突状细胞(dendritic cells,DCs)是一类具有分支或树突状形态的细胞,它们能高效地摄取、加工处理和递呈抗原,主要参与细胞免疫和T细胞依赖的体液免疫反应,在免疫应答中起关键作用,是目前所知的机体内功能最强大的抗原递呈细胞(antigen-presenting cell,APC)。DCs在机体免疫激活和免疫耐受中的作用对于多种临床疾病机制的认识及治疗提供了新的思路。 Summary Dendritic cells (DCs) is known as the most potential and professional antigen presenting cells (APC), it mainly involves in the cellular immunity and T cell dependent humoral immunity, which plays a key role in the immune response and is one of the most hot areas in immunology in recent years. DCs plays a key role in allergic rhinitis (AR) and is one of the most important mechanism of AR treating by sublingual immunotherapy (SLIT). This article reviewed the mechanism of the role of DCs in AR and AR treating by SLIT.
出处 《临床耳鼻咽喉头颈外科杂志》 CAS 北大核心 2014年第14期1089-1092,共4页 Journal of Clinical Otorhinolaryngology Head And Neck Surgery
关键词 树突状细胞 鼻炎 变应性 变应原特异性免疫治疗 调节性T细胞 dendritic cells rhinitis, allergic sublingual immunotherapy regulatory T cells
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