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MMPs在原发性开角型青光眼中的表达 被引量：2

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摘要 基质金属蛋白酶（matrix metalloproteinases,MMPs）是一组锌离子依赖性的内源性蛋白水解酶,其主要功能是降解细胞外基质;基质金属蛋白酶抑制因子是其内源性抑制因子,二者协同以维持细胞外基质的动态平衡.近年研究发现,基质金属蛋白酶对原发性开角型青光眼的发生和发展起重要作用.文中就基质金属蛋白酶在原发性开角型青光眼中的表达及作用进行综述.
作者 周广明 严良
机构地区 上海交通大学附属第六人民医院眼科 上海交通大学附属第六人民医院
出处 《中国实用眼科杂志》 CSCD 北大核心 2014年第7期813-816,共4页 Chinese Journal of Practical Ophthalmology
关键词 原发性开角型青光眼 基质金属蛋白酶 基质金属蛋白酶抑制因子 细胞外基质
分类号 R775.2 [医药卫生—眼科]
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参考文献26

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同被引文献19

  • 1张佳莹,冷非,彭绍民.抗青光眼眼表药物与人结膜成纤维细胞TGF-β、MMP的表达[J].国际眼科杂志,2007,7(5):1294-1297. 被引量：7
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  • 10王翠青,申家泉.开角型青光眼患者房水中MMP-3、TIMP-1的表达及意义[J].山东医药,2008,48(47):22-23. 被引量：1

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中国实用眼科杂志
2014年 第7期

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