紫苏梗的化学成分研究

Study on the Chemical Constituents in the Stem of Perilla frutescens

目的:研究紫苏梗的化学成分。方法:采用硅胶柱色谱、Sephadex LH-20柱色谱等对紫苏梗95%乙醇提取物的乙酸乙酯部位进行分离纯化,根据波谱学数据和理化性质进行结构鉴定。结果:共分离并鉴定了6个化合物,分别为:胡萝卜苷(1)、齐墩果酸(2)、常春藤皂苷元(3)、芹菜素(4)、2,6-二甲氧基苯醌(5)、肌醇(6)。结论:化合物1、3、4、5和6均为首次从紫苏梗中分离得到。

OBJECTIVE： To study the chemical constituents of the stem of Perilla frutescens. METHODS： Silica gel column chromatography and Sephadex LH-20 column chromatography were used for the separation and purification from acetic ether part of 95 % ethanol extract from P. frutescens; and the structure of chemical constituents were identified by spectroscopy data and physi- cochemical characters. RESULTS： 6 compounds were isolated and identified, as daucosterol（1）, oleanolic acid（2）, apigenin （3）, hederagenin （4）, 2, 6-dimethoxy benzene quinone（5）, inositol （6）. CONCLUSIONS： Compoundsl, 3, 4, 5 and 6 are obtained from the stem of P. frutescens for the first time.