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神经精神狼疮机制的研究进展 被引量:3

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摘要 神经精神狼疮(NPSLE)是指系统性红斑狼疮病变侵犯到患者的神经系统而出现的各种神经或精神症状。由于其复杂的发病机制,目前国内对于NPSLE的了解是少而不充分的。近年来新提出的观点有遗传学上某些基因位点的变异、TWEAK信号通路异常表达、神经元代谢异常和退行性病变以及继发因素影响等。文章除了对传统NPSLE机制做补充外,同时对近年来新的观点进行综述,以期为科研和临床诊断与治疗提供新的思路。
出处 《临床和实验医学杂志》 2014年第16期1386-1390,共5页 Journal of Clinical and Experimental Medicine
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