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帕罗西汀治疗幽门螺杆菌相关性胃炎临床分析

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摘要 目的初步探讨帕罗西汀在幽门螺杆菌相关性胃炎治疗中的临床效果。方法 105例幽门螺杆菌阳性胃炎患者随机分为观察组和对照组。观察组60例,予以抗抑郁药物帕罗西汀10μg/d,晨起服用,以及幽门螺杆菌相关性胃炎常规治疗:奥美拉唑胶囊20 mg口服,2次/d;阿莫西林1000 mg,2次/d。对照组45例,予以常规幽门螺杆菌相关性胃炎治疗。4周后对两组治疗效果进行比较。结果抗幽门螺杆菌合并抗抑郁治疗慢性胃炎总有效率为81.67%,高于单纯抗幽门螺杆菌治疗慢性胃炎总有效率68.89%,差异具有统计学意义(P<0.05)。结论在幽门螺杆菌相关性胃炎常规治疗的基础上联合帕罗西汀抗抑郁治疗,对幽门螺杆菌阳性胃炎疗效优于单纯抗幽门螺杆菌治疗,值得进行临床推广。
作者 周贤昌
出处 《中国现代药物应用》 2014年第16期125-126,共2页 Chinese Journal of Modern Drug Application
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