茶多酚对大鼠泌乳性能及抗氧化能力的影响

Effect of tea polyphenols on lactation performance and antioxidant capacity in rats

通过在不同能量条件下,研究茶多酚(TP)对泌乳期大鼠泌乳性能、血液生化指标及抗氧化能力的影响。选取40只SD孕鼠,随机分为4组,每组10个重复,每个重复1只。采用2×2拉丁方设计,分别饲喂:高能日粮(HE),低能日粮(LE),高能日粮+500mg茶多酚/kg饲料(HE-TP),低能日粮+500mg茶多酚/kg饲料(LE-TP),实验期40d。结果表明:添加TP显著提高大鼠的泌乳量及乳腺组织中催乳素(PRL)、雌激素(E2)水平(p<0.05),对采食量没有显著作用。在日粮中添加TP,均可显著降低HE和LE组大鼠血浆TG、GLU和UN水平(p<0.05)。添加TP,HE和LE组大鼠血浆T-AOC、CAT活力显著提高(p<0.05),SOD活力均提高但不显著(p>0.05),MDA水平显著降低(p<0.05)。结论:茶多酚通过提高母鼠的抗氧化能力,减少体内氧化产物,同时调节了泌乳激素水平从而提高了母鼠泌乳性能。

Experiments were conducted to determine the effect of tea polyphenols（TP） on the lactation performance,blood biochemical parameters and antioxidant capacity of lactating rats under different dietary conditions. 40 pregnant SD rats were randomly divided into four groups with 10 repeats in each group and 1 in each repeat. Four kinds of diets were designed by 2×2 Latin square experiment;high-energy diet group（HE）, low-energy diet group（LE）,high-energy diet＋500mg/kg tea polyphenols group（HE-TP）,low-energy diet＋ 500mg/kg tea polyphenols group（LE-TP）. The whole trial period was 40 days. The results showed that：Adding TP significantly increased the lactation yield of postpartum rats and the level of PRL, E2 in mammary gland （p〈0.05）,there＇s no significant effect on feed intake. Adding TP in the diet significantly reduced the level of TG,GLU and UN in plasma in the group of HE and LE（p〈0.05）. After adding TP,the contents of T-AOC and CAT were significantly increased（p〈0.05）,the level of SOD was increased in the group of HE and LE（p〉0.05）, while the level of MDA was significantly reduced（p〈0.05）. Conclusion.Adding tea polyphenols could improve lactation performance of rats by improving antioxidant capacity of rats, reducing oxidative products and adjusting the levels of lactational hormones.