期刊文献+

蛋白质磷酸化对肉品质影响的研究进展 被引量:6

Research advances on protein phosphorylation on meat quality
下载PDF
导出
摘要 蛋白质磷酸化反应是生物界最普遍、最重要的蛋白质翻译后修饰方式。本文综述了磷酸化蛋白质的富集、位点分析、定量分析方法的最新研究进展。从蛋白质磷酸化反应与糖酵解、肌肉收缩、蛋白质降解的关系探讨了蛋白质磷酸化反应对肉品质的影响,并对磷酸化蛋白质组学的发展方向以及蛋白质磷酸化反应在肉品中的研究进行了展望。 Protein phosphorylation is the most common and extensive post-translational modification of proteins. The latest research methods including the enrichment,site analytical and quantitative analytical methods of phosphorylated proteins were summarized in this paper. The effects of protein phosphorylation on meat quality were investigated based on the relationship between protein phosphorylation and glycolysis,muscle contraction and protein degradation. The direction of phosphoproteomics development and research of protein phosphorylation in meat science field were discussed.
出处 《食品工业科技》 CAS CSCD 北大核心 2014年第16期349-352,357,共5页 Science and Technology of Food Industry
基金 公益性行业(农业)科研专项(201303083)
关键词 蛋白质磷酸化 肉品质 糖酵解 肌肉收缩 蛋白质降解 protein phosphorylation meat quality glycolysis muscle contraction protein degradation
  • 相关文献

参考文献39

  • 1钱小红,贺福初.蛋白质组学:理论与方法[M].北京:科学出版社,2003:48-57.
  • 2Cohen P. The origins of protein phosphorylation [J]. Nature Cell Biology, 2002,4 (5) : E 127-E 130.
  • 3Krebs E G. Protein phosphorylation and cellular regulation i (nobel lecture)[J]. Angewandte Chemie International Edition in English, 1993,32(8) : 1122-1 129.
  • 4Fischer E H. Protein phosphorylation and cellular regulation II(Nobel Lecture ) [J]. Angewandte Chemie International Edition in English, 1993,32(8) : 1130-1137.
  • 5王京兰,钱小红.磷酸化蛋白质分析技术在蛋白质组研究中的应用[J].分析化学,2005,33(7):1029-1035. 被引量:16
  • 6赵鹏,徐霞红,周立分,刘欣,聂舟,姚守拙.磷酸化蛋白质分析[J].化学传感器,2011,31(1):3-9. 被引量:9
  • 7李鹏章,王粤博.蛋白质组学中磷酸化肽的常用富集方法[J].化学进展,2012,24(9):1785-1793. 被引量:4
  • 8邓新宇,姜颖,贺福初.磷酸化蛋白质及多肽相关研究的技术进展[J].遗传,2007,29(10):1163-1166. 被引量:12
  • 9Jin M,Bateup H,Padovan J C,et al. Quantitative analysis of protein phosphorylation in mouse brain by hypothesis-driven multistage mass spectrometry[J]. Analytical Chemistry, 2005,77 (24) : 7845-7851.
  • 10Weckerth W, Willmitzer O, Fiehn O. Comparative quantification and identification of phosphoproteins using stable isotope labeling and liquid chromatography/mass spectrometry[J]. Rapid Communication in Mass Spectrometry, 2000, 14 ( 18 ) : 1677-1681.

二级参考文献258

  • 1潘敏鸿,彭瑞云,高亚兵,王水明,马俊杰,王德文,胡文华,张飒,苏镇涛,杨国山.高功率微波辐射对大鼠心肌超微结构和caspase-3表达的影响[J].中华物理医学与康复杂志,2005,27(8):460-463. 被引量:13
  • 2王爽,黄晓峰,王春梅,杨家骥,李珍,黄小军,于华.高功率微波辐照对大鼠血睾屏障通透性的影响[J].中华放射医学与防护杂志,2006,26(2):186-188. 被引量:12
  • 3隋少卉,王京兰,蔡耘,钱小红.磷酸化蛋白质组学分析和定量技术的研究进展[J].生物化学与生物物理进展,2007,34(3):240-245. 被引量:12
  • 4Kumar R,Singh VP,Baker KM.Kinase inhibitors for cardiovascular disease[J].J Mol Cardiol,2007,42(1):1-11.
  • 5Manning G,Whyte DB,Martinez R,et al.The protein kinase complement of the human genome[J].Science,2002,298(5600):1912-1934.
  • 6Force T,Kuida K,Namchuk M,et al.Inhibitors of protein kinase signaling pathways:emerging therapies for cardiovascular disease[J].Circulation,2004,109(10):1196-1205.
  • 7Reiter E,Lefkowitz RJ.GRKs and beta-arrestins:roles in receptor silencing,trafficking and signaling[J].Tre Endocr Met,2006,17(4):159-165.
  • 8Colomer JM,Mao L,Rockman HA,et al.Pressure overload selectively up-regulates Ca2+/calmodulin-dependent protein kinase II in vivo[J].Mol Endocrinol,2003,17(2):183-192.
  • 9Muller JG,Thmpson JT,Edmonson AM,et al.Differential regulation of the cardiac sodium calcium exchanger promoter in adult and neonatal cardiomyocytes by Nkx2.5 and serum response factor[J].J Mol Cell Cardiol,2002,34(15):807-821.
  • 10Wong S,Witte ON.The BCR-ABL story:bench to bedside and back[J].Annu Rev Immunol,2004,22:247-306.

共引文献46

同被引文献38

引证文献6

二级引证文献13

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部