乙型肝炎病毒感染患者生命质量的影响因素分析

Analysis of the factors affecting the quality of life of patients with hepatitis B infections

目的分析影响乙型肝炎病毒(HBV)感染患者生命质量的影响因素,为提高患者的生存质量提供依据。方法选取医院2005年9月-2011年9月收治的214例乙型肝炎患者及同期200例HBV携带者,分别纳入观察组及对照组,对比两组患者生命质量普适性量表SF-36得分差异,并分析影响因素,数据采用SPSS13.0进行分析。结果医院2005年9月-2011年9月共确诊HBV携带者3 129例,其中277例发展为乙型肝炎,发生率8.85%;共对11 597份标本进行HBV检测,发现3 129份HBV携带,感染率26.98%;除躯体疼痛外,观察组其他维度得分均显著低于对照组(P<0.05),两组患者BP维度评分差异无统计学意义;单因素回归分析发现,两组患者婚姻满意度、总胆红素状态、经济状况、肝炎史和并发疾病差异有统计学意义(P<0.05)。结论乙型肝炎患者生命质量会受到严重影响,而婚姻不满意、总胆红素升高、经济状况差、有肝炎史及有并发疾病是导致其生命质量较差的独立危险因素,在今后的防治中,应重视患者的心理疏导、并发症处理及费用减免等多项干预措施,改善患者的生命质量。

OBJECTIVE To analyze factors that influence the quality of life in patients with hepatitis B infections, so as to provide a basis for improving the quality of life of patients. METHODS From Sep. 2005 to Sep. 2011, 214 cases of patients in our hospital with hepatitis B and the same period 200 cases of HBV carriers were selected and divided into observation group and control group. Life quality universal scale SF-36 score difference was to mrared, and to analyze the influence factors. SPSS13.0 software was used for statistical analysis. RESULTS There were HBV carriers in 3129 cases in our hospital from Sep. 2005 to Sep. 2011, including 277 cases developing to hepatitis B, accounting for 8.85%. A total of 11597 patients were detected by HBV, 3129 cases of HBV were found to carry, and the infection rate was 26.98% except for body pain, the observation group scores were significantly lower than those in the control group （P〈0.05）, two groups of BP dimension score had no significant difference; single factor regression analysis found that, there were significant differences between two groups of marital satisfaction, totat bilirubin, economic status, history of hepatitis and concurrent disease （P〈 0. 05）; multiple regression analysis found that, dissatisfied marriage, increased total bilirubin, bad economic situation, hepatitis history and concurrent disease were the leading causes of independent risks of the poor quality of life in patients with hepatitis B （P〈0.05） factors. CONCLUSION The life quality of patients with hepatitis B will be seriously affected, but dissatisfied marriage, increased total bilirubin, bad economic situation, hepatitis history and concurrent disease are the leading causes of independent risk factors for the poor quality of life. In the future prevention and control, doctors should pay more attention to patients with psychological counseling, treatment of complications and cost reduction, intervention measures, to improve the patients＇ quality of life.