产妇生殖道支原体属感染耐药性分析

Analysis on infection status and drug resistance of mycoplasmas isolated from puerpera genital tract

目的研究产妇生殖道支原体属感染的支原体属类型及耐药性,并对预防对策进行探讨,指导临床控制产妇生殖道支原体属感染。方法选取医院2011年3月-2012年9月的生殖道支原体属感染产妇96例,分离培养支原体属,并对支原体属的耐药性进行药敏试验。结果 96例生殖道支原体属感染产妇的生殖道分泌物经培养分析,单纯解脲脲支原体(Uu)感染67例占65.79%;单纯人支原体(Mh)感染7例占7.29%;Uu+Mh感染22例占22.92%;Uu对克拉霉素和普那霉素的敏感性较高,分别为95.52%和92.54%;Mh对普那霉素、克拉霉素和罗红霉素的敏感性较高,分别为100.00%、100.00%和100.00%;Uu+Mh对普那霉素和克拉霉素的敏感性较高,分别为90.91%和86.36%。结论产妇生殖道支原体属感染发生时,应及时做支原体属分离培养及药敏试验,选择耐药率低、灵敏度高的抗菌药物进行及时的治疗。

OBJECTIVE To study the types and resistance of mycoplasma in puerpera genital tract infections, and discuss some prevention measures so as to＇guide clinical control of mycoplasma infection in puerpera genital tract. METHODS A total of 96 puerpera with mycoplasma infections in genital tract were selected, and pathogenic mycoplasma were separated and cultured, then the mycoplasma drug resistance and sensitivity were tested. RESULTS A total of 96 samples of genital tract secretions from puerpera with mycoplasma infection in genital tract were analyzed, the results showed there were 67 cases of simple Ureaplasrna urealyticum （Uu） infection accounting for 65.79%, 7 cases of simple Mycoplasma hominis （Mh） infection accounting for 7.29%, and 22 cases of Uu plus Mh infection accounting for 22.92%. Uu had a higher sensitivity for Clarithromycin and pristinamycin, with the sensitivity rate of 95.52% and 92.54 % respectively. Mh had a higher sensitivity for pristinamycin, clarithromycin and Roxithromycin, with the sensitivity rate of 100.00%, 100.00% and 100.00% respectively. Uu plus Mh had a higher sensitivity for Pristinamyein and Clarithromycin, with the sensitivity rate of 90. 91% and 86. 36% respectively. CONCLUSION When mycoplasmas infection of genital tract occurred in puerpera, isolation, culture and drug sensitivity test of myeoplasmas should he performed and timely treatment should be initialized with selection of antimicrobial drugs of low resistance rates and high sensitivity.