吸氧联合生姜鼻疗法预防乳腺癌化疗后急性呕吐的疗效观察

Observation on curative effect of oxygen combined with ginger nasal therapy for prevention of acute vomiting in breast cancer patients after chemotherapy

[目的]观察吸氧联合生姜鼻疗法预防乳腺癌化疗后急性呕吐的疗效。[方法]将60例乳腺癌首次使用TAC方案化疗病人,随机分为观察组与对照组,观察组在常规给予止吐药物治疗外予吸氧联合生姜鼻疗法,对照组予常规止吐药物治疗,运用世界卫生组织(WHO)关于化疗药物急性及亚急性毒性反应分级标准评估疗效,并对比观察组与对照组急性呕吐的发生程度。[结果]两组急性呕吐发生程度及有效率比较,观察组有效率为86.66%,对化疗后急性呕吐的缓解程度高于对照组,差异有统计学意义(P<0.01)。[结论]在病人化疗开始给予吸氧联合生姜鼻疗法能有效预防乳腺癌化疗后急性呕吐反应。

Objective：To observe the curative effect of oxygen combined with ginger nasal therapy for the prevention of acute vomiting in breast cancer patients after chemotherapy.Methods：A total of 60cases of breast cancer patients receiving the first TAC chemotherapy were randomly divided into observation group and control group,patients in observation group was given oxygen combined with ginger nasal therapy on the basis of routine antiemetic drug treatment,and patients in control group received routine antiemetic therapy.The acute and subacute chemotherapy drugs＇ toxicity classification standard of in WHO was used to assess the curative effect,and to compare the incidence of acute vomiting between observation group and control group.Results：In acute vomiting degree and efficiency comparison,the effective rate in observation group was 86.66%,the alleviation degree of acute vomiting in observation group after chemotherapy was higher than that in control group,and the difference was statistically significant（P0.01）.Conclusion：oxygen combined with ginger nasal therapy at the beginning of patients＇ chemotherapy can effectively prevent acute vomiting in patients with breast cancer after chemotherapy.