2型糖尿病中医证型与甲状腺功能的关系研究

Study of Relationship between Type 2 Diabetes in Different TCM Syndromes and Thyroid Function

目的:研究2型糖尿病中医证型与甲状腺功能的关系,指导2型糖尿病患者甲功筛查,促进甲功异常的早期诊断及干预。方法:选取2型糖尿病阴虚热盛型、湿热困脾型、气阴两虚型、阴阳两虚型及血瘀脉络型患者各30例,对照组30例,测定甲状腺功能,统计分析中医各证型与甲状腺功能之间的关系。结果:2型糖尿病甲状腺功能减退患病率高于对照组,其中,阴阳两虚型甲状腺功能减退患病率高于其余4型,差异均具有统计学意义(P<0.05)。结论:甲状腺功能可以在一定程度上反映2型糖尿病病情及中医证型演变,2型糖尿病尤其是阴阳两虚型患者,进行常规甲状腺功能尤其是FT3的检测,对促进甲状腺功能减退的早期诊断和治疗有着积极意义。

Objective：To study the relationship between type 2 diabetes （T2DM） in different TCM syndromes and thy- roid function and to guide thyroid function screening and promote early diagnosis and treatment of thyroid dysfunction. Methods ：30 cases for each syndrome were selected, including yin deficiency and excess heat syndrome, damp heat syn- drome, qi and yin deficiency syndrome, stagnated blood syndrome and deficiency of yin and yang syndrome. 30 cases of healthy people were selected as the normal control group （NCG）. Thyroid function was measured and the relationship between TCM syndromes and thyroid function were analyzed. Results ：The prevalence of hypothyroidism of T2DM group was higher than that of NCG and the prevalence of hypothyroidism of deficiency of yin and yang syndrome was higher than that of other four syndromes with a significant difference （ P 〈 0. 05 ）. Conclusion ： Thyroid function can reflect the severity of T2DM and the TCM syndrome to a certain extent. In patients of T2DM ,especially deficiency of yin and yang syndrome,the detection of thyroid function especially FI3, has a positive significance to promote early diagnosis and treatment of hypothyroidism.