摘要
Spermatogonial stem cells （SSCs） reside on the basement membrane of the seminiferous tubules in mammalian testes （Nagano et al., 1998）. After isolation and purification of SSCs from mouse testis, SSCs can be cultured in vitro to derive germ-line stem cells （GSCs） which have the ability of proliferation over 2 years （Kanatsu-Shinohara et al.. 2003;
Spermatogonial stem cells （SSCs） reside on the basement membrane of the seminiferous tubules in mammalian testes （Nagano et al., 1998）. After isolation and purification of SSCs from mouse testis, SSCs can be cultured in vitro to derive germ-line stem cells （GSCs） which have the ability of proliferation over 2 years （Kanatsu-Shinohara et al.. 2003;
基金
supported by the National Basic Research Program of China(No.2013CB947903)
the National Natural Science Foundation Project Outstanding Young Scholars(No.31322036)
