心理行为干预合黄连提取液灌肠治疗溃疡性结肠炎28例疗效观察

Clinical efficacy of psychological and behavioral intervention and enema with Coptis chinensis extract liquid in treatment of ulcerative colitis:a report of 28 cases

目的:观察心理行为干预合黄连提取液灌肠治疗溃疡性结肠炎的临床疗效。方法:将轻度溃疡性结肠炎患者56例随机分为治疗组和对照组各28例。两组在常规治疗的基础上,治疗组采用心理行为干预联合黄连提取液肠内给药治疗,对照组给予美沙拉嗪栓便后纳入肛门治疗。两组均以10d为1个疗程,共治疗6个疗程。结果:有效率、显效率及总有效率治疗组均高于对照组,差异均有统计学意义(均P<0.05)。结论:心理行为干预合黄连提取液肠内给药治疗溃疡性结肠炎在缓解症状和改善身心状况方面效果明显,为一种治疗溃疡性结肠炎的好疗法,且毒副作用小,易被广大患者所接受。

Objective：To observe the clinical efficacy of psychological and behavioral intervention and enemawith Coptis chinensis extract liquid in the treatment of ulcerative colitis. Methods：Fifty - six patients with mild ulcerative colitis were randomly divided into treatment group （n = 28） and control group （n = 28）. In addition to conventional treatment, the treatment group received psychological and behavioral intervention and enema with Coptis chinensis extract liquid, and the control group was given mesalazine suppositories put in the anus. Both groups received six courses of treatment （ 10 d per course）. Results ： The treatment group had significantly higher response rate, marked response rate, and overall response rate than the control group （ P 〈0. 05 for all）. Conclusion ： For patients with ulcerative colitis, psychological and behavioral intervention and enema with Coptis chinensis extract liquid are effective in relieving symptoms and improving physical and mental status, so it is a good therapy for ulcerative colitis. In addition, it has few toxic or side effects and thus can be widely accepted by patients.