椎体裂隙征与经皮椎体后凸成形术后手术椎体再骨折及相关因素分析

Predictive risk factors and analysis of its possible mechnisim for cemented vertebral refracture after percutaneous kyphoplasty

目的 分析经皮椎体后凸成形术（PKP）术后手术椎体再骨折的危险因素并分析其可能的发生机制。方法 将自2010-01-2012-07收治的72例单节段骨质疏松性椎体压缩骨折采用PKP治疗的患者纳入研究,根据术后手术椎体是否发生再骨折将患者分为再骨折组和非再骨折组。结果 所有患者获得随访12-42个月,平均24.5个月。随访期内共发生手术椎体再骨折15.3%（11/72）,2组仅椎体裂隙征和骨质疏松骨密度T值差异有统计学意义（P〈0.05）,而性别、年龄、体重、骨水泥注入量、术前Cobb角、椎体前缘高度丧失值及术后椎体前缘高度恢复率差异均无统计学意义（P〉0.05）。结论 椎体裂隙征和骨质疏松可能与PKP术后手术椎体再骨折有关。

Objective To identify risk factors for refracture of cemented vertebral after pereutaneous kyphoplasty （PKP）, andto analyze its possible mechanism. Methods A retrospective analysis of 72 patients who underwent pereutaneous kyphoplastyfor osteoporotic vertebral compression fracture between January 2010 and July 20）12 was conducted. All patients wereclassified into refracture group and non-refracture group according to cemented vertebra/refracture or not after percutaneouskypboplasty. Results All patients were followed up for 12-42 months, 24.5 months on average. The incidence of cementedvertebral refracture after percutaneous kyphoplasty was 15.3%（11/72）. The intervertebral c｜eft（IVC） and bone mineral density -T scores were significant as a result of researching various factors related to vertebra/refracture （P 〈0.05）. Other factors werenot signiiicant（P 〉0.05）. Conclusion Patients who had IVC preoperative magnetic resonance imaging and osteoporotic itselfmay be related to cemented vertebra/refracture after percutaneous kypboplasty.