低辐射剂量低对比剂浓度在320排CT冠脉成像中的应用

Application of low radiation dose and low concentration of contrast agent in 320-CT coronary angiography

目的:探讨低辐射剂量低对比剂浓度冠脉成像的可行性。方法:对临床拟诊为冠心病的200例患者随机分为A、B、C 3组,A组(120 kV,270 mgI/mL)65例,B组(120 kV,350 mgI/mL)65例,C组(100 kV,270 mgI/mL)70例。采用320排CT行前瞻性心电门控扫描,评价试验所得到的3组图像质量以及患者所接受的有效辐射剂量。结果:3组图像冠脉评分无显著差异(P>0.5),图像噪声和增强效果有明显差异(P<0.05),但都可满足诊断。患者所接受的辐射剂量有显著差异(P<0.01),C组是其中的最低值组。结论:低辐射剂量低对比剂浓度可用于CT冠脉成像,并且具有明显的优越性。

Objective：To evaluate the effect of low radiation dose and low concentration of contrast agent for coronary computed tomography （CCTA） with 320-detector CT.Methods：200 patients with clinically suspected coronary disease were randomly divided into A,B,C three groups.Group A（120 kV,270 mgI/mL） 65 cases,group B（120 kV,350 mgI/mL） 65 cases,group C （100 kV,270 mgI/mL） 70 cases,and performed CCTA with prospective ECG gating by using 320-detector CT.Image and the optimal radiation dose were evaluated.Results：Coronary images of three groups had no significant difference （P〉0.5）.Image noise and enhancement was significantly different（P〈0.05）,but it can be used for diagnosis.The radiation dose received by the patient had a significant difference （P〈0.01）,and the dose received by group C is the lowest.Conclusion：The 320 multi-slice CT with low radiation dose and low concentration of contrast agent can be used for CCTA,and has obvious advantages.