摘要
患者女,6岁。自出生起全身出现线状和漩涡状痣样色素沉着、局限性掌跖角化。躯干斑疹组织病理示:角化过度,棘层轻度增生,基底层色素增加,未见明显色素失禁,真皮浅层血管周围散在稀疏淋巴细胞浸润。心脏彩超示:左室稍大,二尖瓣轻度返流。诊断为线状和漩涡状痣样过度黑素沉着病伴局限性掌跖角化病。
A 6-year-old girl presented with linear and whorled brown patch on her trunk and focal p^moplantar kera- toderma after birth. A biopsy of trunk macula revealed that epidermal hyperkeratosis and mild acanthosis, increased melanin in the basal layer without liguefaction degeneration, and superficial perivascular sparse lymphohistiocytic infiltrates in dermis. In addition, CDFI showed left atrium moderate enlargement with mitral mild regurgitation. The diagnosis of linear and whorled nevoid hypermelanosis with focal palmoplantar keratoderma was made.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2014年第8期826-828,共3页
The Chinese Journal of Dermatovenereology
