肝硬化患者医院感染的危险因素分析

Risk factors of nosocomial infections in patients with cirrhosis

目的探讨肝硬化患者医院感染的相关危险因素,为临床提供可靠治疗依据。方法回顾性分析2011年5月-2013年5月医院收治734例肝硬化患者临床资料,调查影响医院感染的相关因素,所有数据采用SPSS13.0进行统计分析。结果调查的734例患者中有79例发生医院感染,感染率10.76%;感染部位以下呼吸道感染与泌尿生殖感染最多,分别占45.65%、28.26%;分离出104株病原菌,以大肠埃希菌与金黄色葡萄球菌居多,分别占37.50%、25.96%;年龄大、住院时间长、肝功能不全、使用多种抗菌药物、侵入性诊疗操作均是肝硬化患者医院感染的高危因素。结论肝硬化患者医院感染的危险因素较多,容易发生医院感染,医院要通过加强消毒工作、严格执行无菌操作等措施降低医院感染的发生率。

OBJECTIVE To investigate related risk factors for nosocomial infections in patients with cirrhosis to provide a reliable basis for clinical treatment.METHODS Clinical data of 734 patients with cirrhosis from May 2011 to May 2013 were retrospectively analyzed to explore the related factors affecting nosocomial infections.All data were analyzed with SPSS 13.0.RESULTS In the 734 patients,79patients had nosocomial infections,the nosocomial infection rate was 10.76%.For infection sites,lower respiratory tract infection and genitourinary infections were the most,accounting for 45.65% and 28.26 %.Totally 104 pathogens were isolated,mainly including Escherichia coli and Staphylococcus aurous,accounting for 37.50% and 25.96%.Older age,long hospital stay,hepatic insufficiency,the use of multiple antimicrobial agents,the use of invasive treatment operations were the high risk factors for nosocomial infections in patients with cirrhosis.CONCLUSION The risk factors for nosocomial infections in patients with cirrhosis are various,who are prone to have infections,the hospital should strengthen disinfection work and strictly implement aseptic procedures and other measures to reduce the incidence of nosocomial infections.