胎膜早破与新生儿感染相关性研究

Correlation research on premature rupture of membranes and neonatal infections

目的探讨胎膜早破与新生儿感染相关性,并提出相对应的措施,以期提高临床诊治水平。方法随机选取2011年12月-2012年5月360例胎膜早破合并新生儿感染患儿为研究对象,作为观察组,选取同时期350例无胎膜早破合并新生儿感染作为对照组,比较胎膜早破与感染之间的关系,采用SPSS13.0软件进行分析。结果观察组新生儿败血症有23例占6.57%、早产45例占12.86%、重症感染103例占28.61%;实验室检查指标、病原体分布与正常的无胎膜早破新生儿差异有统计学意义(P<0.05)。结论密切观察胎膜早破的情况,早期进行相关辅助检查并积极治疗可降低新生儿感染的发生。

OBJECTIVE To investigate the correlation between premature rupture of membranes（PROM）and neonatal infections,and propose corresponding measures to improve the clinical diagnosis and treatment.METHODS Totally 360 cases of PROM combined neonatal infections in May 2012-Dec.2011 were randomly selected as the research subject and set as the observation group,meanwhile,350 cases of neonatal infections without PROM during the same period were selected as the control group to compare the relationship between PROM and infections.The analysis was conducted with SPSS 13.0.7 RESULTS In the observation group,there were sepsis in 23cases（6.57%）,prematurity in 45（12.86%）,severe infection in 103（28.61%）.There were significant differences in laboratory examination indexes and pathogens compared to the normal newborns without PROM（P0.05）.CONCLUSION Close observation for PROM,early associated auxiliary examinations and aggressive treatment can reduce the incidence of neonatal infections.