南山藤叶非甾体类化学成分研究

Non-Steroidal Constituents from the Leaves of Dregea volubilis

目的:研究南山藤叶中的非甾体类化学成分,阐明其物质基础。方法:利用硅胶、凝胶、MCI等色谱技术手段,对南山藤叶80%乙醇提取物的乙酸乙酯萃取部位进行分离,运用MS、NMR等波谱方法确定所得化合物结构。结果:从萝藦科南山藤属植物南山藤的干燥叶中分离鉴定了9个化合物:蒲公英赛醇(1),谷甾醇(2),丁香树脂醇(3),梣皮树脂醇(4),栎焦油酸(5),β-胡萝卜苷(6),橙黄胡椒酰胺苯甲酸酯(7),吲哚-3-甲醛(8),橙黄胡椒酰胺乙酸酯(9)。结论:酰胺类化合物7和9为首次从萝蘑科中分得。

To study the non-steroidal constituents of the leaves from Dregea Volubilis and to clarify the material basis. Methods： The ethyl acetate extracts of the 80% ethanol extracts of Dregea volubilis were separated by means of silica gel, Sephadex LH-20 and MCI chromatography. The compounds isolated from the plant were identified by spectrum methods such as MS and NMR. Results： Nine non-steroidal compounds were isolated from the leaves of Dregea volubilis （Asclepiadaceae） and identified as：taraxerol （1）, β-sitosterol （2）, syringaresinol （3）, medioresinol （4）, queretaroic acid （5）, β-daucosterol （6）, auranti-amide benzoate （7）, indole-3-carboxaldehyde （8） and aurantiamide acetate （9）. Conclusion： Among them, amide （or dipeptide） -type compounds 7 and 9 were firstly obtained from this family.