麻黄碱对非去极化肌松药起效时间的影响

The effects of ephedrine on the onset time of non-depolarizing muscular relaxant

背景 麻黄碱作为一种拟交感神经药,可通过增加心输出量加速非去极化肌松药到达神经肌肉接头的速度,进而缩短肌松药的起效时间. 目的 回顾麻黄碱在缩短非去极化肌松药起效时间方面的临床应用进展,为临床麻醉提供参考. 内容 主要对麻黄碱的作用机制、给药剂量、给药时机、副作用等方面予以阐述. 趋向 麻黄碱为临床麻醉中缩短非去极化肌松药的起效时间提供一种实用的方法.

Background Ephedrine,as a kind of sympathomimetic agent,can accelerate the delivery of non-depolarizing muscle relaxant to the neuromuscular junction by increasing cardiac output,thus shortening the onset time of muscle relaxant.Objective To review the advances of ephedrine use in shortening the onset time of non-depolarizing muscle relaxant and provide reference for clinical anesthesia.Content This article mainly elaborates the mechanism of ephedrine on shortening the onset time of non-depolarizing muscle relaxant,dosage,medication timing and adverse reactions.Trend Ephedrine has been proved to provide a practical way for shortening the onset time of non-depolarizing muscle relaxant in clinical anesthesia.