期刊文献+

微波消解-原子荧光光谱法分析肺癌患者全血中硒

Analysis of Selenium in Blood of Patients with Lung Cancer by Microwave Digestion-Atomic Fluorescence Spectrometry
下载PDF
导出
摘要 目的探讨肺癌患者血样中硒含量的变化。方法采集肺癌组和对照组血样,用硝酸、过氧化氢混合液微波消解样品,采用原子荧光光谱法测定血样中硒的含量。结果肺癌组和对照组硒平均质量浓度分别为0.087、0.123 mg/L。结论肺癌患者血样硒含量明显降低,缺硒可能是导致肺癌高发的重要因素。 Objective The paper investigates the change of the selenium content in the blood samples of patients with lung cancer. Methods The writer applies miscible liquids of nitric acid and hydrogen peroxide to the digestion of the collected blood samples from lung cancer group and the control group,using atomic fluorescence spectrometry to determine the content of selenium in blood samples. Results The average content of selenium in the lung cancer group and control group in average content of selenium are 0. 087 mg /L and 0. 123 mg /L respectively. Conclusion The content of selenium significantly lowered in the blood samples collected from patients with lung cancer. Selenium deficiency may be an important factor leading to high incidence of lung cancer.
出处 《广东微量元素科学》 CAS 2014年第7期28-31,共4页 Trace Elements Science
基金 合肥市科技局基金项目
关键词 微波消解 原子荧光光谱法 肺癌 microwave digest AFS lung cancer Se
  • 相关文献

参考文献10

二级参考文献57

  • 1姚莉,段玉峰.微量元素硒与人体健康[J].中国食物与营养,2004,10(7):50-52. 被引量:16
  • 2任峰玲,郭雄.硒的特性、毒性及在某些国家的现状[J].国外医学(医学地理分册),2004,25(3):117-119. 被引量:14
  • 3王加恩,任荣富,梁河,张七金,黄永庆.安吉梅溪地氟病与地质地球化学环境分析[J].微量元素与健康研究,2004,21(6):42-44. 被引量:4
  • 4RAJEEV KS,JAMES AW,GEORGINA FM,et al.Selenoprotein expression is essential in endothelial cell development and cardiac muscle function[J].Nueromuscular Disorders,2007(17):135-142.
  • 5KRYUKOV GV,CASTELLANO S,NOVOSELOV SV,et al.Characterization of mammalian selenoproteomes[J].Science,2003(300):1439-1443.
  • 6YANT LJ,RAN Q,RAO L,et al.The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults[J].Free Radic Biol Med,2003(34):496-502.
  • 7HILL KE,ZHOU J,MCMAHAN WJ,et al.Deletion of selenoprotein P alters distribution of selenium in the mouse[J].J Biol Chem,2003(278):13640-13646.
  • 8SCHOMBURG L,SCHWEIZER U,HOLTMANN B,et al.Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues[J].Biochem J,2003(370):397-402.
  • 9CHRISTOFFOLETE MA,LINARDI CCG,DE J L,et al.Mice with targeted disruption of the Dio2 gene have cold-induced overexpression of the uncoupling protein 1 gene but fail to increase brown adipose tissue lipogenesis and adaptive thermogenesis[J].Diabetes,2004(53):577-584.NG L,GOODYEAR RJ,WOODS CA,et al.Hearing loss and retarded cochlear development in mice lacking type 2 iodothyronine deiodinase[J].Proc Natl Acad Sci USA,2004(101):3474-3479.
  • 10NG L, GOODYEAR RJ, WOODS CA, et al. Hearing loss and retarded cochlear development in mice lacking type 2 iodothyronine deiodinase[J]. Proc Natl Acad Sci USA ,2004(101) :3474-3479.

共引文献108

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部