血清微量元素与胃蛋白酶原联合检测在胃癌早期诊断中的应用进展

Application Progress of Serum Trace Elements and Pepsinogen Combined Detection in the Diagnosis of Early Gastric Cancer

胃癌是中国最常见的恶性肿瘤,且病死率居恶性肿瘤的首位。寻找一种有效的筛查方法进行胃癌早期诊断及治疗可以明显改善胃癌的预后及降低病死率。近年来,很多研究证实血清中某些微量元素和胃蛋白酶原(PG)在体内水平的变化与胃癌的发生、发展密切相关。通过检测胃癌患者体内微量元素与PG的水平,可以对胃癌进行辅助诊断。该文着重阐述血清微量元素与PG联合检测在胃癌早期诊断中的应用。

Gastric cancer is the most common malignant tumor in China, and the mortality rate ranks the first among malignant tumors. Finding an effective screening method for early diagosis and treatment of gastric cancer could significantly reduce the prognosis and the mortality of gastric cancer. In recent years, many studies have confirmed that the changes of some trace elements and pepsinogen levels in serum in the bodies are closely related with occurrence and development of gastric cancer. Detecting the content of trace elements and pepsinogen in bodies of gastric cancer patients can make auxiliary diagnosis of gastric cancer. Here is to make a review focusing on the application of serum trace elements and pepsinogen combined detection in early diagnosis of gastric cancer.