摘要
目的分析影响急性百草枯(PQ)中毒的预后因素,探讨合理的救治方案。方法将36例PQ中毒患者分为存活组(12例)和死亡组(24例),对其临床资料进行回顾性分析。结果 26例患者中死亡24例,死亡率66.67%。死亡组的服毒剂量、就诊时间、白细胞计数、并发症发生率、急性生理学及慢性健康评分Ⅱ(APACHEⅡ)均明显高于存活组。两组比较差异有统计学意义(P<0.05)。结论急性PQ中毒病死率极高,及早就诊及洗胃,适时反复血液净化,早期应用抗氧化损伤药物和肾上腺皮质激素等综合治疗措施,可改善预后及降低死亡率。
Objective To analyze the factors of prognosis of acute paraquat （PQ） poisoning and investigate rational treatment.Methods 36 cases of PQ poisoning patients were divided into the survival group （12 cases） and the death group （24 cases）.Results There were 12 survival and 24 death.The mortality rate was 66.67%.The death group was significantly higher than the survival group in poison dose,treatment time,white blood cell count,incidence of complications,acute physiology and chronic health evaluation Ⅱ （APACHE Ⅱ）.The difference was statistically significant （P〈0.05）.Conclusion Acute PQ poisoning is a high mortality rate disease and comprehensive treatment measures such as early treatment,gastric lavage,timely repeated blood purification,early application of anti-oxidative damage drugs and adrenocorticotropic hormone can improve outcomes and reduce mortality.
出处
《西部医学》
2014年第8期1059-1060,1063,共3页
Medical Journal of West China
关键词
百草枯中毒
预后
综合治疗
Paraquat poisoning
Prognosis
Comprehensive treatment
