期刊文献+

抑郁症治疗成败的相关因素 被引量:3

原文传递
导出
摘要 目前研究显示,抑郁症是多个易患基因和环境因素相互作用的产物[1].抑郁症不仅是一种慢性的、复发性疾病,还可能是一种进展性疾病,持续脑内功能改变会促使结构也发生相应的变化[2].抑郁症不仅与脑内神经环路改变有关,还与内分泌、免疫和自主神经功能的变化有关[3-4].抑郁症可能不是一个简单的综合征,而是一组复杂的疾病,涉及脑与躯体不同水平的改变,因此增加了治疗的难度.我们将从阻碍抑郁症患者获得更好治疗的原因,以及如何成功治疗两个方面,以整体、综合的观点来阐述抑郁症.
出处 《中华精神科杂志》 CAS CSCD 北大核心 2014年第4期247-249,共3页 Chinese Journal of Psychiatry
基金 上海市卫生局科研课题(20114358) 国家自然科学基金青年基金(81201033)
  • 相关文献

参考文献39

  • 1lqamer D.Genetics.Rethinking behavior genetics[ J].Science,2002,298:71-72.
  • 2Kendler KS,Thornton LM,Gardner CO.Stressful life events and previous episodes in the etiology of major depression in women:an evaluation of the ' kindling' hypothesis [ J ].Am J Psychiatry,2000,157:1243-1251.
  • 3Maletic V,Robinson M,Oakes T,et al.Neurobiology of depression:an integrated view of key findings [ J ].Int J Clin Pract,2007,61:2030-2040.
  • 4Maletie V,Raison CL.Neurobiology of depression,fibromyalgia and neuropathic pain [ J ].Front Biosci(Landmark Ed),2009,14:5291-5338.
  • 5Trivedi MH,Rush AJ,Wisniewski SR,et al.Evaluation outcomes with eitalopram for depression using measurement-base care in STAR * D:implications for clinical practice [ J].Am Psychiatry,2006,163:28-40.
  • 6Nierenberg AA,Husain MM,Trivedi MH,et al.Residu symptoms after remission of major depressive disorder witl eitalopram and risk of relapse:a STAR * D report [ J ].Psychol Med,2010,40:41-50.
  • 7姚军,吴香巍,张海音,季建林,李清伟,樊晔,陈华,刘文娟,吴文源.舍曲林与帕罗西汀治疗抑郁症首次发病患者认知功能的相关研究[J].中华精神科杂志,2011,44(4):202-207. 被引量:35
  • 8Conradi HJ,Ormel J,de Jonge P.Presence of individual(residual)symptoms during depressive episodes and periods of remission:a 3-year prospective study [ J ].Psychol Med,2011,41:1165-1174.
  • 9Greco T,Eckert G,Kroenke K.The outcome of physical symptoms with treatment of depression [ J ].J Gen Intern Med,2004,19:813-818.
  • 10Uher R.Genes,environment,and individual differences in responding to treatment for depression[ J].Harv Rev Psychiatry,2011,19:109-124.

二级参考文献38

  • 1苏晖,江开达,徐一峰,宋立升,虞一萍.抑郁症首次发病患者认知功能的研究[J].中华精神科杂志,2005,38(3):146-149. 被引量:85
  • 2Paykel ES.Remission and residual symptomatology in major depression.Psychopathology,1998,31:5-14.
  • 3Maier W,G(a)nsicke M,Weiffenbach O.The relationship between major and subthreshold variants of unipolar depression.J Affect Diord,1997,45(1-2):41-51.
  • 4Broadhead WE,Blazer DG,George LK,et al.Depression,disability days,and days lost from work in a prospective epidemiologic survey.JAMA,1990,264:2524-2528.
  • 5Judd LL,Akiskal HS,Maser JD,et al.A prospective 12-year study of subsyndromal and syndromal depressive symptoms in unipolar major depressive disorders.Arch Gen Psychiatry,1998,55:694-700.
  • 6Shirayama Y,Chen ACH,Nakagawa S,et al.Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression.J Neurosci,2002,22:3251-3261.
  • 7Siuciak JA,Lewis DR,Wiegand SJ,et al.Antidepressant-like effect of brain-derived neurotrophic factor (BDNF).Pharmacol Biochem Behav,1997,56:131-137.
  • 8Duman CH,Schlesinger L,Kodama M,et al.A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment.Biol Psychiatry,2007,61:661-670.
  • 9Kermani P,Hempstead BB.Brain-derived neurotrophic factor:a newly described mediator of angiogenesis.Trends Cardiovasc Med,2007,17:140-143.
  • 10Lang SB,Stein V,Bonhoeffer T,et al.Endogenous brain-derived neurotrophic factor triggers fast calcium transients at synapses in developing dendrites.J Neurosci,2007,27:1097-1105.

共引文献52

同被引文献34

引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部