止哮方联合西药治疗支气管哮喘随机平行对照研究

Check Xiao Experience Side Joint Random Parallel Control Study Western Medicine Treatment of Bronchial Asthma

［目的］观察止哮方联合西药治疗支气管哮喘疗效。［方法］使用随机平行对照方法,将84例住院患者按病志号抽签简单随机分为两组。对照组42例前3d,泼尼松,15mg/次,1次/d;氨茶碱,0.1g/次,3次/d;3 ～ 6d,泼尼松改为5mg/d,6d后停用泼尼松。治疗组42例1 ～ 5d,止哮方1号（杏仁、葶苈子、桑白皮、干地龙各15g,炙麻黄、麦冬、苏子、法半夏、瓜蒌皮、白果各10g,乌梅、甘草各6g）,1剂/d,水煎至150 ～ 200mL,早晚口服;6d后：止哮方2号（党参、熟地、黄芪各30g,茯苓、沙参、白术、胡桃肉各20g,杏仁、法半夏各10g,麦冬15g,五味子10g,甘草5g）,1剂/d;水煎150 ～ 200mL,早晚口服;西药治疗同对照组。连续治疗30d为1疗程。观测临床症状、EOS、CD4＋、CD8＋、IgE、不良反应。治疗1疗程,判定疗效。［结果］治疗组痊愈14例,显效24例,有效3例,无效1例,总有效率97.62%。对照组痊愈7例,显效15例,有效11例,无效9例,总有效率78.57%。治疗组疗效优于对照组（P＜0.05）。症状积分治疗组有改善（P＜0.01）,症状积分对照组部分改善（P＞0.05,P＜0.01）,治疗组改善优于对照组（P＜0.05,P＜0.01）。［结论］止哮方联合西药治疗支气管哮喘效果显著,值得推广。

[ Objective ] To observe check xiao experience combined western medicine treatment of bronchial asthma effect. [ Methods ] Using random parallel control method, 84 cases of hospitalized patients into two groups according to random number table method. The control group, 42 cases before 3 d prednisone, 15 rag/times, 1 / d. Aminophylline, 0.1 g/time, 3 times/d. 3 ~ 6d, prednisone to 5rag/d, 6 d stopped after prednisone. Treatment group （42cases of 1 ~ 5d, check xiao experience side 1 （ Xingren, Tinglizi, Sangbaipi, Gandilongeach 15g, Zhimahuang, Maidong, Suzi, Fabanxia, Gualoupi, Baiguo 10g, Wumei, Gancao each 6g ） ; l/d, till 150 - 200 mL water, morning and evening oral;after 6 d check xiao experience party 2 （Dangshen, Huangqi 30g, Fuling, Shashen, Baizhu, Hutaoron 20g, Xingren, Fabanxia every 10g, Maidongl5g, Wuweizil0g, Gancao 5g ） agent l/d, Till 150 - 200 mL water, oral sooner or later. Western medicine treatment with the control group. Continuous treatment of 30 d for 1 course of treatment. Observation of clinical symptoms, EOS, CD4 ＋, CD8 ＋, IgE, adverse reactions. As a course treatment, judge curative effect. [ Results ] the treatment group 14 cases cured, 24 cases were markedly improved, 3 cases ineffective in 1 case, and the total effective rate was 97.62%. Control group recovered in 7 cases, 15 cases were markedly effective, effective in 11 cases, 9 no effect, the total effective rate was 78.57%. The treatment group curative effect is better than that of control group （ P〈0.05 ） . Symptom score in treatment group improved （ P 〈0.01 ）, symptoms part to improve the integral control group （P〉O.05, P〈 0.01 ）, the treatment group improved better than that of control group （P〈0.05, P〈0.01 ） . [ Conclusion ] Check xiao experience side combined western medicine treatment of bronchial asthma effect is remarkable, is worth promoting.