河北省2012年麻疹监测结果分析

Analysis of measles surveillance results in Hebei province in 2012

目的监测健康人群麻疹抗体水平,提高实验室监测工作质量,为消除麻疹提供科学依据。方法麻疹IgM和IgG测定用ELISA方法,病原学检测按WHO推荐方法进行。结果河北省2012年麻疹实验室检测疑似麻疹病例血清标本814人份,麻疹IgM抗体阳性16例,阳性率1.97%;同时检测风疹IgM抗体814例,阳性123例,阳性率15.11%。2012年44人份咽拭子标本中分离出1株麻疹病毒,经核苷酸序列分析鉴定,为H1a基因型。结论实验室监测是麻疹监测系统的重要组成部分,对消除麻疹和控制风疹工作发挥着重要作用。河北省目前存在本土麻疹病毒的传播,以散发为主,人群免疫力水平较高。

Objective To monitor the measles antibody levels in healthy people and improve the quality of laboratory monitoring, so as to provide scientific basis for elimination of measles. Methods The IgM and IgG of measles were tested with ELISA, and measles viruses were isolated according to the recommendatory method of WHO. Results A total of 814 serum samples from suspected measles patients were tested for IgM antibody in measles laboratory in Hebei province in 2012. There were 16 IgM positive serum samples, the positive rate was 1.97%. At the same time, 814 serum samples from rubella patients were also tested for IgM antibody, and there were 123 IgM antibody positive samples, with the positive rate of 15.11%. Only one measles virus strain was isolated from 44 throat swabs in 2012, and identified as Hla genotype by nucleotide sequence anal- ysis. Conclusion Laboratory surveillance is a significant part in measles surveillance system, and plays a very important role in measles elimination and rubella control. At present, local wild - viruses of measles is spread in Hebei province, mainly sporadic cases, and immunity level is higher among local population.