摘要
肌钙蛋白是急性冠状动脉综合征重要生物标志物.尤其是近年来兴起的高敏肌钙蛋白在心肌梗死早期诊断和预后评估中起着重要作用.一些国家也发布指南推荐高敏肌钙蛋白的应用.但临床医生和实验室工作人员在使用中仍有许多问题.本文就高敏肌钙蛋白测定和临床应用中的问题,以及国际组织的建议包括统一使用高敏肌钙蛋白名称、单位、确立健康人群选择指南以确定正确的第99百分位值,加以介绍并提出看法.
Troponin is an important biomarker of acute coronary syndrome. Especially high- sensitivity cardiac troponin in recent years played an important role for the early diagnosis and prognosis of myocardial infarction. Recommendations for the use of high-sensitivity cardiac troponin have been issued in some guidelines. But the clinical doctors and laboratory workers still have many problems in practice. Some problems in high-sensitivity cardiac troponin assay and the clinical application were introduced here. Suggestions were also put up from international organizations, including unified high-sensitivity cardiac troponin name, unit, establish healthy population, selection guidelines to identify the 99th percentile value.
出处
《中华检验医学杂志》
CAS
CSCD
北大核心
2014年第7期485-488,共4页
Chinese Journal of Laboratory Medicine
基金
天津市自然科学基金面上项目（12JCYBJC17400）
滨海新区医药卫生科技重点项目（2011BHKZ003）
关键词
肌钙蛋白
生物学标记
敏感性与特异性
心肌梗死
Troponin
Biological markers
Sensitivity and specificity
Myocardial infarction
