鼻咽癌放疗前、后的MRI动态增强曲线的特征

The MRI Dynamic Enhancement Curve Characteristics in Nasopharyngeal Carcinoma Before and After Radiotherapy

目的探讨并鉴别鼻咽癌放疗前、后MRI动态增强的曲线特征。方法收集鼻咽癌患者病例,其中鼻咽癌放疗前68例,放疗后组150例。放疗前组经病理确诊,放疗后组随访复查无复发。采用FL3D_VIBE序列获取2组病例的时间一信号强度曲线(TIC)。结果 TIC曲线类型:放疗前组I型25例,i型23例,ii型17例,iii型3例。放疗后组i型1例,ii型48例,iii型42例,III型59例。最大信号强度可以鉴别放疗前I型、i型、ii型曲线均与放疗后III型、iii型曲线,无法与放疗后ii型曲线鉴别。强化曲线的最大斜率主要可以鉴别放疗前、后ii型曲线。结论鼻咽癌放疗前后的TIC曲线分布有明显特征,并且应用强化曲线的最大斜率可以鉴别放疗前后ii型曲线。

Objective To explore and identify the characteristics of MRI dynamic enhancement curve in nasopharyngeal carcinoma（NPC） before and after radiotherapy. Methods A retrospective study was performed in NPC cases, including 68 cases before radiotherapy, after radiotherapy group 150 cases. Before radiotherapy group were confirmed by pathology, no tumour recurrence was found during follow-up in the after radiotherapy group. The MRI time-intensity curves（TIC） of two groups cases were obtained by FL3D_VIBE sequence. Results TIC curve types： type 1 before radiotherapy group 25 cases, 23 cases of type I and type ii of 17 cases, type iii （3 cases）. After radiotherapy group, 1 case of type I and type ii 48 cases, type iii 42 cases, type iii 59 cases. The maximum signal strength can be identified before radiotherapy type I, type i and type ii curve with type III, type iii curve after radiotherapy, can not be identified with type ii curve after radiotherapy. Strengthen the curve of maximum slope mainly identified before and after radiotherapy of ii type curve. Conclusion Before and after radiotherapy of NPC TIC curve distribution has obvious characteristics, and application of strengthening curve of maximum slope can be identified type ii curves in NPC that before and after radiotherapy.