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氨基末端脑钠肽前体和左室射血分数对慢性心力衰竭预后相关性研究 被引量:3

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摘要 目的:评价N末端脑钠肽(NT-proBNP)在慢性心力衰竭(CHF)诊断及评价近期预后中的临床价值。方法:选择CHF患者75例,根据美国纽约心脏病协会(NYHA)心功能分级标准,采用双向侧流免疫法定量测定NT-proBNP水平,分析NT-proBNP水平与NYHA心功能分级、左心室射血分数(LVEF)、左心室舒张末内径(LVEDD)的关系,观察并随访住院期间和出院后12个月内不良心脏事件的发生率、再住院率及病死率。结果:CHF患者NT-proBNP水平随NYHA级别的增加而升高(P<0.05);NT-proBNP水平升高与LVEF成负相关,与LVEDD成正相关,NT-proBNP水平越高其近期住院率也明显增高,且病情重,死亡率高(P<0.05)。结论:NT-proBNP测定对CHF的诊断有重要临床意义,而且对评价CHF诊断价值及近期预后有重要的临床价值。
出处 《新疆医学》 2014年第6期56-58,共3页 Xinjiang Medical Journal
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