不同糖代谢状态下血清谷氨酰转移酶水平的变化及意义

The variance and significance of glutamyl transpeptidase level under different statuses of glucose metabolism

回顾性分析天津地区不同糖耐量人群资料,分糖耐量正常组、糖耐量异常组、初诊2型糖尿病组.结果显示随着糖代谢异常程度的加重,血清谷氨酰转移酶（GGT）水平逐渐升高,早期胰岛素分泌指数下降,抵抗指数增加,空腹和餐后血糖升高,HbA1C升高,血清GGT水平与早期胰岛素分泌指数呈负相关（P＜0.05）.GGT水平升高是糖代谢异常的独立危险因素.

The crowd were divided to 3 groups according to glucose tolerance：normal glucose tolerance,impaired glucose regulation,and new type 2 diabetes,the data was analyzed.The result showed that as the severity of abnormal glucose metabolism,the serum GGT gradually advanced,early insulin secretion index descended,The levels of resistance index,fasting and postprandial blood sugar,and glycosylated hemoglobin all raised.The serum GGT and early insulin secretion index was inversely correlated.The higher GGT level was an independent risk factors of abnormal glucose metabolism.