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法洛四联症根治手术长期疗效观察 被引量:2

Long-term Outcomes of Surgical Repair of Tetralogy of Fallot
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摘要 法洛四联症是最常见的紫绀型先天性心脏病,其解剖学基础是心室间交通,主动脉骑跨,肺动脉瓣下狭窄,以及由此导致的右心室肥厚。尽管法洛四联症根治术后患者长期生存率很高,但晚期生存患者需要面对严重并发症。进行性肺动脉反流导致的右心衰竭和心律失常是其晚期主要并发症和死亡原因。为此,我们对晚期并发症的发生和治疗的进展进行了综述,强调长期随访的重要性。 Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease. It is characterized by an interventricular communication with an overriding aorta, subpulmonary obstruction, and consequent right ventricular hypertrophy. The potential for late complications is an important concern for growing number of survivors after surgical repair, although long-term survival rates are excellent. Progressive pulmonary valve regurgitation leading to right heart failure and arrhythmias are common late complications and major reasons of mortality. In this review, we focus on research progress of pathogenesis and treatment of late complications after TOF repair, and the importance of long-term follow-up is emphasized.
出处 《中国胸心血管外科临床杂志》 CAS 2014年第4期548-551,共4页 Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
基金 "十二五"国家科技支撑计划项目(2011BAI11B19)~~
关键词 肺动脉瓣 心律失常 长期疗效 法洛四联症 Pulmonary valve Arrhythmia Long-term outcome Tetralogy of Fallot
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