心理动力学取向和药物治疗对边缘性人格障碍的比较研究

Effective Comparison between Psychodynamic Therapy with Pharmacotherapy for Patients with Borderline Personality Disorder

目的:采用随机对照实验法,对心理动力学取向和药物治疗边缘型人格障碍(BPD)的疗效和预后进行比较。方法:根据入组标准选择BPD患者30例,随机分为联合治疗组和药物治疗组各15例,2组均给予药物治疗,联合治疗组还给予心理动力学治疗。应用人格诊断问卷(PDQ-4+)的边缘分量表在治疗前、治疗后、治疗结束后3月和治疗结束后6月进行问卷施测,评估2组疗效和预后。结果:治疗后、治疗后3月及6月,联合治疗组的边缘症状评分低于药物治疗组,有显著差异(P<0.001)。结论:使用心理动力学治疗为主,药物治疗为辅的治疗方法更适合治疗BPD患者。

Objective： To compare the effectiveness of psychodynamic therapy with pharmacotherapy for patients with borderline personality disorder （BPD） by a randomized controlled trial. Method： Thirty BPD patients were al- located either to combined treatment group or pharmacotherapy group in a randomized controlled design. Both the two groups were given pharmacotherapy, and the combined treatment group was given additional psychodynamic therapy. All the participants were assessed by Personality Diagnostic Questionnaires （PDQ-4＋） four times （before the therapy, after the therapy, 3 months and 6 months after completion of the treatment phase）. Results： The PDQ-4＋ scores of combined treatment group were significantly lower than those of pharmacotherapy group at the 4 times （P〈0.001）. Conclusion： The combination of psychodynamic therapy and pharmacotherapy is suitable for the BPD patients.