摘要
主动脉血流仿真可应用于血流运动和部分心血管疾病形成原因分析和风险评价。该文基于核磁共振成像扫描重建的主动脉模型,通过磁共振相位对比成像测量主动脉及主要支脉的时间-流量曲线及血液动力学参数,讨论了不同边界条件下时间-流量曲线、时间-壁面切应力曲线、平均壁面切应力和震荡剪切因子的影响。结果表明:出口边界相对压力为0、采用拟合血流方程的入口条件等边界下计算结果与测量的实际血流曲线作为出口和入口边界条件计算结果差异较大,其中入口参数对壁面切应力、平均壁面切应力和震荡剪切因子计算结果影响较大,出口参数对出口时间-流量曲线影响较大。
Simulations of blood flows in the aorta area provide a better understanding of the hemodynamic blood flow mechanism for evaluating the risk of some cardiovascular diseases.An aorta model was reconstructed from magnetic resonance imaging（MRI）images while the blood flow and hemodynamic parameters in the ascending aorta,the descending aorta and the main peripheral arteries were measured using phase contrast MRI（PC-MRI）.The boundary conditions affected the flow rate,wall shear stress,averaged wall shear stress and the oscillating shear index.The results show that simulations with zero pressure outlets,simulations with fitted input flows and zero pressure outlets,and simulations with fitted input flow and outflow discharges give quite different results.The input flow variations are mainly related to the local and average wall shear stresses and the oscillating shear index.The outlet flows are strongly related to the outlet boundary conditions.
出处
《清华大学学报（自然科学版）》
EI
CAS
CSCD
北大核心
2014年第6期700-705,共6页
Journal of Tsinghua University(Science and Technology)
基金
国家自然科学基金面上资助项目(81070175)
关键词
计算流体力学
主动脉
磁共振相位对比成像
平均壁面切应力
震荡剪切因子
computational fluid dynamics
aorta
phase contrast magnetic resonance imaging（PC-MRI）
averaged wall shear stress
oscillating shear index
