急性呼吸道感染相关病毒组学研究进展

Research advance in the viromics of acute respiratory infections

随着人类社会的发展,人与大自然、野生动物的接触日益频繁,人员沟通旅行逐年增多,新发传染病频发。其中呼吸道传染病最为突出,2003年SARS疫情暴发,使人们重新认识了冠状病毒,并开始意识到越来越多的动物源病毒可能跨种传播[1]。2009年墨西哥、美国暴发甲型H1N1流感,夺走了数万人的生命,表明流感病毒的变异、重组速度加快,新发病毒的检测和疫苗的研发需要不断的更新[2-3]。

Acute respiratory infections account for high morbidity and mortality especially in the elderly and the children and most of the infections are virus etiology. The research on the viromics of acute respiratory infec tions is important for the disease prevention and control. With the development of the next-generation sequencing technology, the exploring of the viromics of this disease becomes realistic. The review briefly summarized the techniques and advances of acute respiratory infection in the field of viromics study.