多层螺旋CT灌注成像在孤立性肺结节鉴别诊断中的应用研究

Application study of multilayer spiral CT perfusion imaging in differential diagnosis of solitary pulmonary nodules

目的：研究应用多层螺旋CT鉴别诊断孤立性肺结节的价值。方法行全肺平扫，平扫层厚5mm；随后将最大的结节病灶选定，行HRCT扫描，层厚1～2mm，并同时开始扫描以及灌注。结果良性SPN、炎性SPN以及恶性SPN患者的灌注成像结果并不一致，其中PS、BF以及BV存在显著性差异（P＜0.05），MTT的差异不明显（P＞0.05）。结论在对良性SPN、炎性SPN以及恶性SPN进行诊断鉴别的过程中，CT灌注成像技术能够发挥重要作用。

Objective To study the application value of multilayer spiral CT in the identification and diagnosis of solitary pulmonary nodules（SPN）. Methods The whole lung plain scan was conducted and the layer thickness of plain scan was 5 mm. Then the largest nodule lesion was selected to receive HRCT scan and the layer thickness was 1-2 mm. Scan and perfusion were conducted at the same time. Results The patients with benign SPN, inflammatory SPN and malignant SPN did not have consistent perfusion imaging results, of which PS, BF and BV had significant differences（P〈0.05） and MTT did not have significant difference（P〉0.05）. Conclusion In the diagnosis and identification of benign SPN, inflammatory SPN and malignant SPN, CT perfusion imaging technique can play an important role.