某综合性医院多重药耐药菌感染调查

INVESTIGATION OF INFECTIONS OF MULTIPLE- DRUG RESISTANT ORGANISMS IN A GENERAL HOSPITAL

目的了解医院住院患者多重药耐药菌感染现状及临床分布特征,为临床合理使用抗菌药物提供依据。方法利用实验室信息系统(LIS)和查看病人,对某县级综合性医院住院患者多重耐药菌感染情况进行了调查与分析。结果该医院在两年时间内,从住院患者送检标本中共检出病原菌2 308株,其中有1 334株为多重耐药菌株,占57.80%。在检出的鲍曼不动杆菌、肺炎克雷伯菌、大肠埃希菌等菌株中,多重耐药菌株占50%以上,多重耐药菌感染的患者主要分布于重症监护病房、呼吸科和神经内科。多重耐药菌感染的患者,在医院获得感染占64.75%,社区获得感染占56.11%。结论该医院住院患者送检标本中检出的病原菌中,多重耐药菌比例较高,应加强细菌耐药性的监测和抗菌药物使用管理。

Objective To know the current situation and distribution characteristics of Multiple- Drugs Resistant Organisms（ MDROs） in inpatients of a local hospital,for grounding reasonable usage of antibiotics. Methods MDROs were monitored through Laboratory Information System（ LIS） and the clinical distribution characteristics were analyzed. Results2308 strains were detected in hospitalizations in two years,of which 1334 strains（ 57. 8%） were MDROs. MDROs were more than 50% in strains of Staphylococcus aureus,Klebsiella pneumoniae,Escherichia coli,Acinetobacter baumannii and Pseudomonas aeruginosa. Patients were mainly distributed in ICU,respiratory department and neurology department. The detection rates of hospital and communal MDROs infections were 65. 32% and 56. 01% respectively. Conclusion Monitoring of bacterial drug resistance and regulation of antibiotics should be strengthened due to the high prevalence of MDROs in hospitalization.