血液灌流联合血液透析治疗慢性心肾综合征维持性透析患者顽固性低血压的临床疗效

Clinical effect of hemoperfusion combined with hemodialysis on treatment of refractory hypotension in hemodialysis patients with chronic heart and kidney syndrome

目的探讨血液灌流联合血液透析治疗慢性心肾综合征维持性透析患者顽固性低血压的疗效。方法比较本院血液净化中心14例慢性心肾综合征维持性透析合并顽固性低血压患者行血液灌流联合血液透析治疗后血压的变化,分析联合治疗后患者低血压发生率及透析始末时的平均血压变化。结果随着联合治疗次数的增加,第13周低血压发生率较第1周时显著下降(P<0.05);随着联合治疗次数的增加,透析始末时的平均血压均逐渐升高,第1周与第13周时比较差异有统计学意义(P<0.05)。结论血液灌流联合血液透析可有效改善慢性心肾综合征维持性透析顽固性低血压患者血压水平。

Objective To explore the effect of hemoperfusion combined with hemodialysis on treatment of refractory hypotension in hemodialysis （HD） patients with chronic heart and kidney syndrome.Methods 14 HD patients with chronic heart and kidney syndrome were collected,the changes of blood pressure before and after combination therapy were compared,and incidence of hypotension and mean blood pressure were analyzed.Results With the increasing of number of combined therapy,the incidence of hypotension in the thirteenth week was significantly lower than that in the first week （P ＜ 0.05）.With the increasing of number of combined therapy,the mean blood pressure increased gradually,and there was significant difference between the thirteenth week and the first week.Conclusion Hemoperfusion combined with hemodialysis can effectively correct blood pressure of HD patients with chronic heart and kidney syndrome.