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外周血调节性T细胞表达水平与卵巢上皮癌预后的相关性 被引量:2

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摘要 卵巢上皮癌(EOC)是最常见的妇科恶性肿瘤之一,其常规治疗手段包括原位切除及术后放化疗.尽管许多患者在常规治疗后,其腹水症状可得到缓解,但大多数患者会出现复发情况,因而目前EOC逐渐成为致死率最高的妇科肿瘤之一.许多研究证实,调节性T细胞(Tregs)能够下调非特异性免疫水平,促进肿瘤发展,对于患者的治疗和康复有不良影响.有研究认为FoxP3+Tregs对于EOC的预后有影响,但大多相关研究是通过病理切片或实验进行研究,缺乏临床研究,目前只明确在部分EOC病理过程中可能发生卵巢Tregs原位积累,但有关外周血Tregs与EOC的关系则并未明晰.本研究选取2010年1月-2013年6月本院收治的卵巢癌患者50例,对比治疗前后外周血Tregs水平,现报告如下.
作者 赵春梅
出处 《实用临床医药杂志》 CAS 2014年第11期182-184,共3页 Journal of Clinical Medicine in Practice
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