摘要
本课题采用半乳糖与壳聚糖为起始原料制备N-乳糖酰化壳聚糖,通过红外光谱IR证明在壳聚糖C2-NH2引入乳糖酸,得到酰化产物。利用TG对其进行物理性质分析,发现改性后的壳聚糖热稳定性增强,有望成为新型壳聚糖载体。
N-galaetose chitosan (NCG) was synthesized by acylation of chitosan with galaetose anhydride. IR showed the reaction occurred on the amine group of chitosan. The structure and physical behaviors were characterized by TG. The results confirmed the introduction of galatose in the position of C2 --NH2 of chitosan and that after the modification of chitosan, because of the decline of hydrogen bond capacity, their thermal stability reduced. It is expected to become the new chitosan carrier.
出处
《黑龙江科学》
2014年第5期14-15,18,共3页
Heilongjiang Science
基金
黑龙江省科学院青年创新基金项目
关键词
壳聚糖
半乳糖
制备
Chitosan
galaetos
preparation